Peripheral neuropathies, a multidimensional and practical approach to a complex condition

Authors

DOI:

https://doi.org/10.21615/cesmedicina.6250

Keywords:

peripheral neuropathy, electrodiagnostic, axonal, demyelinating, therapy

Abstract

Introduction: peripheral neuropathies comprise a wide range of entities affecting one or multiple peripheral nerves in any of their functional categories. Methods: review of the literature on the subject, by searching for articles in Pubmed and Google Scholar databases published in the last 21 years, without language restriction, excluding descriptive studies and case reports. Results: peripheral neuropathies have a prevalence of 2 % to 3 %, and can be caused by infectious etiologies, inflammatory diseases, immunological, neoplastic disorders, exposure to toxins, drugs and nutritional deficiencies. Their diagnosis depends on clinical judgment. The application of laboratory and electrodiagnostic studies can adequately classify these entities. Treatment depends on the underlying entity and should include a multimodal approach. Conclusions: establishing strategies for prevention, early detection and treatment allows for potential recovery and decreases costs for the health system.

Downloads

Download data is not yet available.

Author Biographies

Alex Jhonier Imbachí Salamanca, Universidad del Cauca

Especialista en Medicina Interna, Universidad del Cauca, Colombia. 

Karen Liseth Chito Castro, Pontifica Universidad Javeriana de Cali

Residente del posgrado de Medicina Familiar, Pontificia Universidad Javeriana de Cali, Colombia. 

Juan David Orozco Burbano, Universidad del Cauca

Especialista en Medicina Interna, Universidad del Cauca, Colombia. 

Tomás Omar Zamora Bastidas, Universidad del Cauca

Especialista en Neurología. Docente departamento de Medicina Interna, Universidad del Cauca, Colombia. 

References

Forcada ALG. Neuropathies, radiculopathies and plexopathies. Med. 2019;12(75):4423–36. DOI: 10.1016/j.med.2019.03.023

Doughty CT, Seyedsadjadi R. Approach to Peripheral Neuropathy for the Primary Care Clinician. Am J Med. 2018;131(9):1010–6. DOI: 10.1016/j.amjmed.2017.12.042

England JD, Asbury AK. Peripheral neuropathy. Lancet. 2004;363:2151–61. DOI: 10.1016/S0140-6736(04)16508-2

Pradilla G, Vesga BE, Leon-Sarmiento FE, Bautista LE, Núñez LC. Neuroepidemiología en el oriente colombiano. Rev Neurol. 2002;34(11):1035–43. DOI: https://doi.org/10.33588/rn.3411.2001486

Gordois A, Scuffham P, Shearer A, Oglesby A, Tobian JA. The Health Care Costs of Diabetic. Diabetes Care. 2003;26:1790–1795. DOI: 10.2337/diacare.26.6.1790

Hoffman EM, Robb JM, Sauver JLS, Dyck PJ, Klein CJ. Impairments and comorbidities of polyneuropathy revealed by population-based analyses. Neurology. 2015; 84(16):1644-51. DOI: 10.1212/WNL.0000000000001492

Alport AR, Sander HW. Clinical Approach to Peripheral Neuropathy. Contin Lifelong Learn Neurol. 2012;18:13–38. DOI: 10.1212/01.CON.0000411546.13207.b1

Rajabally YA, Stettner M, Kieseier BC, Hartung HP, Malik RA. CIDP and other inflammatory neuropathies in diabetes - Diagnosis and management. Nat Rev Neurol. 2017;13(10):599–611. DOI: 10.1038/nrneurol.2017.123

Liu X, Xu Y, An M, Zeng Q. The risk factors for diabetic peripheral neuropathy: A meta-analysis. PLoS One. 2019;14(2):1–16. DOI: 10.1371/journal.pone.0212574

Gómez-Utrero E, Navarro Expósito F. Protocolo de manejo clínico de la neuropatía en el paciente oncológico. Med. 2017;12(31):1883–6. DOI: 10.1016/j.med.2017.04.008

Rosenbaum E, Marks D, Raza S. Diagnosis and management of neuropathies associated with plasma cell dyscrasias. Hematol Oncol. 2018;36(1):3–14. DOI: 10.1002/hon.2417

Leonhard SE, Mandarakas MR, Gondim FAA, Bateman K, Ferreira MLB, Cornblath DR, et al. Diagnosis and management of Guillain–Barré syndrome in ten steps. Nat Rev Neurol. 2019;15(11):671–83. DOI: 10.1038/s41582-019-0250-9

Querol L, Devaux J, Rojas-Garcia R, Illa I. Autoantibodies in chronic inflammatory neuropathies: Diagnostic and therapeutic implications. Nat Rev Neurol. 2017;13(9):533–47. DOI: 10.1038/nrneurol.2017.84

Bril V, Katzberg HD. Acquired immune axonal neuropathies. Contin Lifelong Learn Neurol. 2014;20(5):1261–73. DOI: 10.1212/01.CON.0000455882.83803.72

Mathis S, Magy L, Le Masson G, Richard L, Soulages A, Solé G, et al. Value of nerve biopsy in the management of peripheral neuropathies. Expert Rev Neurother. 2018;18(7):589–602. DOI: 10.1080/14737175.2018.1489240

Graf J, Imboden J. Vasculitis and peripheral neuropathy. Curr Opin Rheumatol. 2019;31(1):40–5. DOI: 10.1097/BOR.0000000000000559

Collins MP, Hadden RD. The nonsystemic vasculitic neuropathies. Nat Rev Neurol. 2017;13(5):302–16. DOI: 10.1038/nrneurol.2017.42

Basantsova NY, Starshinova AA, Dori A, Zinchenko YS, Yablonskiy PK, Shoenfeld Y. Small-fiber neuropathy definition, diagnosis, and treatment. Neurol Sci. 2019;40(7):1343–50.

Watson JC, Dyck PJB. Peripheral Neuropathy: a practical approach to diagnosis and symptom management. Mayo Clin Proc. 2015;90(7):940–51. DOI: 10.1016/j.mayocp.2015.05.004

Politei JM, Durand C, Schenone AB. Small fiber neuropathy in fabry disease: A review of pathophysiology and treatment. J Inborn Errors Metab Screen. 2016;4:1–5. DOI: 10.1177/2326409816661351

Stüve O, Zettl U. Neuroinflammation of the central and peripheral nervous system: An update. Clin Exp Immunol. 2014;175(3):333–5. DOI: 10.1111/cei.12260

Barrell K, Smith AG. Peripheral Neuropathy. Med Clin North Am. 2019;103(2):383–97. DOI: 10.1016/j.mcna.2018.10.006

Iodice V, Sandroni P. Autonomic neuropathies. Contin Lifelong Learn Neurol. 2014;20(5):1373–97. DOI: 10.1212/01.CON.0000455875.76179.b1

Hughes RAC. Peripheral neuropathy. BMJ. 2002;324:466–9. DOI: 10.1136/bmj.324.7335.466

Castelli G, Desai KM, Cantone RE. Peripheral Neuropathy: evaluation and differential diagnosis. Am Fam Physician. 2020;102(12):732–9. Disponible en: https://www.aafp.org/afp/2020/1215/p732.html

Gasparotti R, Padua L, Briani C, Lauria G. New technologies for the assessment of neuropathies. Nat Rev Neurol. 2017;13(4):203–16. DOI: 10.1038/nrneurol.2017.31.

Siao P, Kaku M. A Clinician’s Approach to Peripheral Neuropathy. Semin Neurol. 2019;519–30. DOI: 10.1055/s-0039-1694747

Smith Nold C, Nozaki K. Peripheral neuropathy: Clinical pearls for making the diagnosis. J Am Acad Physician Asisstants. 2020;33(1):9-15. DOI: 10.1097/01.JAA.0000615460.45150.e0

Barrell K, Smith AG. Peripheral Neuropathy. Med Clin North Am. 2019;103(2):383–97. DOI: 10.1016/j.mcna.2018.10.006

Botas Velasco M, Cervell Rodríguez D, Rodríguez Montalbán AI, Vicente Jiménez S, Fernández de Valderrama Martínez I. Actualización en el diagnóstico, tratamiento y prevención de la neuropatía diabética periférica. Angiologia. 2017;69(3):174–81. DOI: 10.1016/j.angio.2016.06.005

Lünemann JD, Nimmerjahn F, Dalakas MC. Intravenous immunoglobulin in neurology-mode of action and clinical efficacy. Nat Rev Neurol. 2015;11(2):80–9. DOI: 10.1038/nrneurol.2014.253

Blaes F. Diagnosis and therapeutic options for peripheral vasculitic neuropathy. Ther Adv Musculoskelet Dis Rev. 2015;7(2):45–55. DOI: 10.1177/1759720X14566617

Loprinzi CL, Lacchetti C, Bleeker J, Cavaletti G, Chauhan C. Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: ASCO Guideline Update. J Clin Oncol. 2020;38(28):3325-3348; DOI: 10.1200/JCO.20.01399

Staff NP, Grisold A, Grisold W, Windebank AJ, Clinic M. Chemotherapy-induced peripheral neuropathy: a current review. Ann Neurol. 2018;81(6):772–81. DOI: 10.1002/ana.24951

Callaghan B, Price R, Chen K, Feldman E. The Importance of rare subtypes in diagnosis and treatment of peripheral neuropathy a review. Jama Neurol. 2015;1–9. DOI: 10.1001/jamaneurol.2015.2347

Portada Revista Ces Medicina 36(1) 2022

Downloads

Published

2022-05-11

How to Cite

Imbachí Salamanca, A. J., Chito Castro, K. L., Orozco Burbano, J. D., & Zamora Bastidas, T. O. (2022). Peripheral neuropathies, a multidimensional and practical approach to a complex condition. CES Medicina, 36(1), 46–58. https://doi.org/10.21615/cesmedicina.6250

Issue

Vol. 36 No. 1 (2022): CES Medicina

Section

Artículos de reflexión

License

Copyright (c) 2022 CES Medicina

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Derechos de reproducción (copyright)

Cada manuscrito se acompañará de una declaración en la que se especifique que los materiales son inéditos, que no han sido publicados anteriormente en formato impreso o electrónico y que no se presentarán a ningún otro medio antes de conocer la decisión de la revista. En todo caso, cualquier publicación anterior, sea en forma impresa o electrónica, deberá darse a conocer a la redacción por escrito.

Plagios, duplicaciones totales o parciales, traduccones del original a otro idioma son de responsabilidad exclusiva de los autores el envío.

Los autores adjuntarán una declaración firmada indicando que, si el manuscrito se acepta para su publicación, los derechos de reproducción son propiedad exclusiva de la Revista CES Medicina.

Se solicita a los autores que proporcionen la  información completa acerca de cualquier beca o subvención recibida de una entidad comercial u otro grupo con intereses privados, u otro organismo, para costear parcial o totalmente el trabajo en que se basa el artículo.

Los autores tienen la responsabilidad de obtener los permisos necesarios para reproducir cualquier material protegido por derechos de reproducción. El manuscrito se acompañará de la carta original que otorgue ese permiso y en ella debe especificarse con exactitud el número del cuadro o figura o el texto exacto que se citará y cómo se usará, así como la referencia bibliográfica completa.

Article metrics
Abstract views
Galley vies
PDF Views
HTML views
Other views

Altmetric